|LETTER TO EDITOR
|Year : 2018 | Volume
| Issue : 3 | Page : 152
Submandibular synovial sarcoma mimicking a vascular lesion: A rare case report
Mahmood Dhahir Al-Mendalawi
Department of Paediatrics, Al-Kindy College of Medicine, University of Baghdad, Baghdad, Iraq
|Date of Web Publication||27-Sep-2018|
Mahmood Dhahir Al-Mendalawi
Department of Paediatrics, Al-Kindy College of Medicine, University of Baghdad, P. O. Box 55302, Baghdad Post Office, Baghdad
Source of Support: None, Conflict of Interest: None
|How to cite this article:|
Al-Mendalawi MD. Submandibular synovial sarcoma mimicking a vascular lesion: A rare case report. SRM J Res Dent Sci 2018;9:152
I spent a wonderful time reading the interesting case report by Kumar et al. on the submandibular synovial sarcoma (SS) mimicking a vascular lesion in an Indian patient. In the view of the rarity of the tumor to affect an unusual site, I presume that the authors should consider altered immune status in the studied patient. Among altered immune states, infection with human immunodeficiency virus (HIV) has a major priority. My presumption is based on the following point. It is explicit that patients infected with HIV are more vulnerable to various tumors compared with immunocompetent counterparts. The increased vulnerability has been attributed to many factors, including co-infection with oncogenic viruses, immunosuppression, and life extension due to the use of antiretroviral treatment. Among tumors, SS has been reported in HIV-infected individuals. To my knowledge, HIV infection is a worrisome health hazard in India. Although no recent data are yet present on the HIV seroprevalence in India, the available data pointed out to 0.26% HIV seroprevalence compared with a global average of 0.2%. Hence, planning for the diagnostic set of CD4 lymphocyte count and viral overload measurements was envisaged in the studied child. If that diagnostic set was achieved and it demonstrated HIV infection, the case in question could be certainly considered the second novel case report of HIV-associated SS in India. The first case was of primary pleuro-pulmonary SS in HIV positive Indian patient.
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Conflicts of interest
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| References|| |
Kumar N, Dhiman NK, Singh S, Vishwakarma AK. Submandibular synovial sarcoma mimicking a vascular lesion: A rare case report. SRM J Res Dent Sci 2018;9:100-2. [Full text]
Valencia Ortega ME. Malignancies and infection due to the human immunodeficiency virus. Are these emerging diseases? Rev Clin Esp 2018;218:149-55.
Shah UB, Joshi S, Ghorpade SV, Gaikwad SN, Sundrani RM. Primary pleuro-pulmonary synovial sarcoma. Indian J Chest Dis Allied Sci 2010;52:169-72.
Paranjape RS, Challacombe SJ. HIV/AIDS in India: An overview of the Indian epidemic. Oral Dis 2016;22 Suppl 1:10-4.